Endocrine Abstracts

Introduction: Coronavirus infection COVID19 spread by Sars-Cov-2 virus were announced by WHO as a pandemics in the end of 2019. As shown in many studies virus affects whole body, particularly endocrine system. There were information about thyroid disturbances after COVID19 infection. Fergana valley of Uzbekistan is an endemic region with high degree of iodine deficiency. The aim of our study were investigate impact of COVID19 on thyroid function in people living in iodine defi...

Introduction: Malignant tumors of the thyroid gland are common in the field of endocrinology as an oncological disease. The diagnosis of thyroid cancer (TC) is based on sonographic and cytological methods. The widespread use of TI-RADS classification and the Bethesda System for Reporting Thyroid Cytopathology proposed by the American College of Radiology (ACR) and the U.S. National Cancer Institute (NCI) relatively significantly increases diagnostic accuracy. In this study dia...

Introduction: Diabetes Mellitus (DM) is one of the Global pandemics despite to new knowledges and methods of prevention and therapy intensively increased among children, adolescents and adults. Many studies shown the role of the gastrointestinal microbiocenosis in the development and clinical future of DM. Gut microbiota produce numerous bioactive molecules, which can act locally and secreted into bloodstream. The aim of our study were evaluation of gut microbiota in children ...

Introduction: Past years with increasing of duration of life, improving of treatment and increasing of life longevity and new knowledges about Diabetes Mellitus pathogenesis and treatment rise interest to reproduction in these women, especially with type 1 DM. Well known, that late puberty, abnormal menstrual cycle, pregnancy and childbirth pathology, infertility. The aim of our study was investigate the functional state of reproductive system in woman with DM1.<p class="a...

Introduction: Renin angiotensin system play a crucial role in the development of Diabetes Mellitus and its complications. According many studies, plasma renin level increased at the DM. However, mechanisms of its elevation is not clear yet. The aim of our study was compare plasma renin level in DM1 and DM2 patients and its relationship with glycemic control.Material and Methods: In 44 people with DM1 and 85 with DM2 whose admitted into Hospital of the Re...

Introduction: The purpose of this work was monitor the frequency of determination and compare the levels of parathyroid hormone in blood plasma in people on programmed hemodialysis.Material and methods: Data from medical records of 465 patients on programmed hemodialysis who were admitted to the Republican Centre of Nephrology and Kidney Transplantation were analyzed. Patients according to reason of end stage of renal failure were divided into 3 groups d...

Introduction: Metabolic disturbances at the Diabetes Mellitus (DM) leads to structural and functional abnormalities of the cell plasma membrane due to changes in the lipid content and composition, especially phospholipids. Plasmalogens are unique group of phospholipids with alcohol and ether bounds, presented in a few papers. We hypothesis their involvement into pathogenesis of DM.Material and methods: We studied the content of Plasmalogens in blood plas...

Background: Obesity is worldwide epidemics and the main risk factor for many diseases. Traditional methods of prevention and treatment of obesity often unfavorable and patients undergo to alternative treatment such as bariatric surgery. To better understanding the pathogenesis of obesity, we aimed to analyse the main abnormalities in blood serum in patients accepted to bariatric surgery.Material and Methods: 27 patients (13 men and 14 women) with obesity...

Background: Increasing of the level of circulating Antithyroid autoantibodies suggested about autoimmune destruction in thyroid gland and not always depends from thyroid status. We aimed to study the frequency of circulating antithyroid autoantibodies (ATAB) in people with the different thyroid diseases.Material and Methods: In 25 people with high level of circulating ATAB blood serum TSH, T3, T4, glucose, ALAT, protein, albumin levels were measured. Thy...

IntroductionNaKATPase is membrane bound enzyme, necessary for maintenance of the cell potential and volume, ion flow, neuronal signal transduction. Previous studies showed decreasing of its activity in patients with diabetes mellitus (DM). Mechanisms regulated enzymes activity in DM is not clear yet. We proposed that glycemia is a main regulator of NaKATPase activity in erythrocytes at the DM.Material and methods<p class="abste...